Tag Archives: Dr. Burzynski

Burzynski: Peer-Reviewed Published Articles (most recent to 2015)

List of recently published peer-reviewed articles related to
Antineoplastons and Burzynski’s “personalized cancer therapy”

ANTINEOPLASTONS:

2015

A Phase II Study of Antineoplastons A10 and AS2-1 in Adult Patients with Primary Brain Tumors—Final Report (Protocol BT-09)

Link: http://www.scirp.org/Journal/PaperInformation.aspx?PaperID=61444

———-

A Phase II Study of Antineoplastons A10 and AS2-1 in patients with recurrent Anaplastic Astrocytoma—Final Report (Protocol BT-15)

Link: http://www.ccsenet.org/journal/index.php/cco/article/view/47383

———-

A Phase II Study of Antineoplastons A10 and AS2-1 in patients with Brainstem Gliomas.
The Report on Non-Diffuse Intrinsic Pontine Glioma (Protocol BT-11)

Link: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=55563#.VTRM6hPF_t1

———-

A Phase II Study of Antineoplastons A10 and AS2-1 in Adult Patients
With Newly-Diagnosed Anaplastic Astrocytoma – Final Report (Protocol BT-08)

Link: http://www.ccsenet.org/journal/index.php/cco/article/view/42461

———-

2014

———-

The response and survival of children with recurrent diffuse intrinsic pontine glioma based on
phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma

Pubmed link: http://www.ncbi.nlm.nih.gov/pubmed/24718705

READ FULL PDF

———-

A Phase II Study of Antineoplastons A10 and AS2-1 in Children with High-Grade Glioma.
Final Report (Protocol BT-06), and Review of Recent Trials

Abstract: http://www.scirp.org/journal/PaperInformation.aspx?paperID=46242#.VMF91i7F-Qw

READ FULL PDF

———-

A Phase II Study of Antineoplastons A10 and AS2-1 in Adult Patients with Recurrent Glioblastoma Multiforme:
Final Report (Protocol BT-21)

Abstract: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=49564#.VMF-dS7F-Qw

READ FULL PDF

———-

A Phase II Study of Antineoplastons A10 and AS2-1 in Children with Recurrent, Refractory or Progressive Primary Brain Tumors—
Final Report (Protocol BT-22)

Abstract: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=49568#.VMF-wy7F-Qw

READ FULL PDF

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Recurrent Glioblastoma Multiforme— A Strategy for Long-Term Survival

Abstract: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=49566#.VMF_SS7F-Qw

READ FULL PDF

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The Effect of Antineoplastons A10 and AS2-1 and Metabolites of Sodium Phenylbutyrate
on Gene Expression in Glioblastoma Multiforme

Abstract: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=49471#.VMF_jy7F-Qw

READ FULL PDF

**********

PERSONALIZED GENE-TARGETED

2015

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A Case of Sustained Objective Response of Recurrent/Progressive Diffuse Intrinsic Pontine Glioma
with Phenylbutyrate and Targeted Agents

Abstract: http://www.scirp.org/journal/PaperInformation.aspx?paperID=52985#.VMF9NS7F-Qw

READ FULL PDF

———-

2014

Preliminary Findings on the Use of Targeted Therapy in Combination with Sodium Phenylbutyrate
in Colorectal Cancer after Failure of Second-Line Therapy—A Potential Strategy for Improved Survival

Abstract: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=51577#.VMF_6S7F-Qw

READ FULL PDF

———-

Preliminary Findings on the Use of Targeted Therapy in Combination with Sodium Phenylbutyrate in
Advanced Malignant Mesothelioma: A Strategy for Improved Survival

Abstract: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50986#.VMGALS7F-Qw

READ FULL PDF

———-

Preliminary Findings on the Use of Targeted Therapy in Combination with Sodium Phenylbutyrate in
Recurrent Advanced Pancreatic Cancer—A Potential Strategy for Improved Survival

Abstract: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50936#.VMGAci7F-Qw

READ FULL PDF

———-

Preliminary Findings on the Use of Targeted Therapy with Pazopanib and Other Agents in Combination
with Sodium Phenylbutyrate in the Treatment of Glioblastoma Multiforme

Abstract: http://www.scirp.org/journal/PaperInformation.aspx?paperID=52600#.VMGAtC7F-Qw

READ FULL PDF


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Just released: BURZYNSKI: CANCER CURE COVER-UP (2016)

CLICK: (2016): Instantly watch the new BURZYNSKI: CANCER CURE COVER-UP (2016) 1 hour, 50 min

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Texas Medical Board vs. Dr. Burzynski and employed doctors | Nov. 19, 2015


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On November 19, 2015 The Texas Medical Board (TMB) opens the latest hearings against Dr. Burzynski and other doctors at the Burzynski Clinic alleging dubious charges in an effort to keep the clinic from treating any more people suffering from cancer and thus attempting to keep current and future cancer patients from making their own treatment decisions by seeking Dr. Burzynski as a treatment option.

Why are they doing this? Because they can. The TMB has exhausted all avenues trying to keep Burzynski from using his FDA-sanctioned invention, Antineoplastons, they went all the way up to the State Supreme Court and lost in that attempt — so now the TMB has to focus on Burzynski’s “personalized cancer therapy” (as covered in “Burzynski: Part II”) as a new plan of attack.

Be sure to follow The Burzynski Movie Facebook Page, Twitter, and Subscribe to this documentary series YouTube Channel to stay up-to-date during the trial. Eric Merola, the director and producer of the Burzynski: Cancer Is Serious Business Documentary Series will be there on Thursday and Friday (Nov. 19-20) to cover the opening dates and report back to the public throughout the day.

If you live in the Austin, TX area and would like to come out to show your support, be sure to follow this project’s Facebook page or email us here. Otherwise you can show up at the 300 West 15th St, 4th FL, Austin, TX 78701 address before 9am or throughout the day.

Teresa Kennett, who was cured by Burzynski’s Antineoplastons in the 1990s has started a Change.org petition, if you wish to sign it here. Learn more about Teresa’s story here.

Watch Teresa’s full testimony in Congress below

In case you missed some of the recent updates related to the Burzynski Saga, here are a few updates from 2015:

September 23, 2015 Update:

August 28, 2015 Update:

January 29, 2015 Update:

Getting annoyed by those who believe the negative propaganda?

Here is a link to recent peer-reviewed studies – here.

Here is a link describing the organized Astroturf campaign currently underway – here.

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Jessica Ressel-Doeden – Inoperable Diffuse Intrinsic Brainstem Glioma (DIPG) – Cured with Medical Records

Jessica Ressel-Doeden was diagnosed with a diffuse, intrinsic, childhood brainstem glioma (DIPG) in March of 1996 at age eleven.

According to the available data there has not been a single case of a verified cure (5-year survival) with patients diagnosed with diffuse (inoperable) childhood brainstem glioma treated with radiation and/or chemotherapy in any FDA-supervised experimental clinical trial in the history of medicine. Dr. Burzynski’s Antineoplastons hold the only cures to date—with a cure rate in some studies as high as 27.5% [PDF of original report, table page 172] + [Chemo/Rad – PubMed 2005] [ANP – PubMed 2003] [ANP – PubMed 2006] [ANP – Cancer Therapy 2007]

[The Lancet 2006 explains grim outlook – “survival remains static”].

** April 2014 Peer-reviewed clinical trial report for DIPG using Antineoplastons **

Following her initial diagnosis, the Ressel’s were informed that the only method approved by the FDA to “treat” her condition would be radiation. The radiologist informed the family that radiation would be shot “through the ears, burning her healthy cells from the outside in—causing permanent deafness, all of the hair around her ears would be gone—never grow back, her ears would become deformed and burnt, her pituitary gland would be destroyed—the gland that allows a human to grow and develop, and if she survived the treatment she would become a vegetable and incapable of taking care of herself.”

Considering that radiation treatment has never been shown to cure a single patient with her condition, combined with the devastating side effects such a treatment would inflict on an eleven-year old child—her parents declined the radiation treatment offered by her oncologists and decided to have Jessica treated by Dr. Burzynski instead.

Medical Records

1. Diagnosis: Jessica underwent an MRI on April 10, 1996 at the St. Louis Children’s Hospital which revealed a tumor in her brainstem. Her diagnosis was also confirmed on May 7, 1996 upon initial consultation with Dr. Burzynski. She had multiple MRIs after she was admitted into the Burzynski Clinic. There is also multiple third-party confirmations of diagnosis by physicians from the Springfield Clinic and the Missouri Eye Institute demonstrated by letters written to the Ressel’s insurance company.

2. Recovery: On May 8, 1996, Jessica began antineoplaston treatment. Her tumor disappeared and reappeared multiple times throughout the course of 14 months after the start date of treatment. On June 27, 1997, her tumor disappeared permanently. She has had multiple MRIs of the brain since that time which have all been negative for tumor recurrence—with the last MRI being May 20, 2005. Read Jessica’s treatment summary here. Read Jessica’s tumor measurements here. After her full recovery, the Mid-Atlantic Open MRI of Springfield, MO confirmed her tumor-free MRIs from 11/97 to 5/98 [PDF all medical records and sources for this paragraph].

3. FDA-supervised clinical trial data comparing chemotherapy and radiation treatment to antineoplaston treatment in patients with diffuse, intrinsic, childhood brainstem glioma. It has been clearly demonstrated that of 107 patients treated with chemotherapy and radiation with this type of tumor: 0.9% of these patients were cancer-free at the end of treatment, with no patient surviving 5 years after diagnosis. Of the patients treated with antineoplastons with this type of tumor: 27.5% of them were cancer-free at the end of treatment, with 27.5% of the patients living at least 5 years after diagnosis. Therefore, Jessica Ressel’s recovery after being treated with antineoplastons is not a mere anecdotal case (See sources from start of this post above).

Most would assume that such results would be front page news across the world, or would be grounds for Dr. Burzynski to receive the Nobel Prize in medicine. Sadly, these peer-reviewed results have been universally ignored by mainstream medicine.

Raising the Money to Receive Her Antineoplaston Treatment

Unfortunately, most insurance companies will not cover antineoplaston treatment. The Ressel family had to come up with $6000 per month to pay for her treatment all by themselves. The high cost of antineoplaston treatment is directly due to the United States government’s refusal to allow any tax-payer money to be granted to fund the FDA-supervised clinical trials that Jessica participated in—while simultaneously granting PhRMA tens of millions of dollars to fund similar FDA-supervised clinical trials with inferior outcomes.

Below is a TV news footage montage from 1996-1997 covering Jessica’s story, fundraisers and more:

The Ronald McDonald House Charities®

During our interview with the Ressel family, Robin said that she “had called the Ronald McDonald House to see if we’d be able to stay there, because we were going to have to stay in Houston for a while, I was talking to a volunteer on the phone—when I mentioned we had an eleven-year old we were taking to see Dr. Burzynski and we needed a place to stay for a couple of weeks—you could hear whispering going on in the background, the volunteer was being prompted what to say, and The Ronald McDonald House refused to allow us to stay there because we weren’t an M.D. Anderson patient. I felt bad for the volunteer, you could tell she was being told what to say.” Dan followed up by saying “There are a lot of programs out there, but I will never give a dime to the Ronald McDonald House. We were in a desperate situation, and they refused us because we were a patient of Dr. Burzynski”.

Joining the Fight in Preserving Burzynski’s Freedom

Jessica Ressel was being treated by Dr. Burzynski in 1996, several months after the FDA’s 5th grand jury against Dr. Burzynski resulted in an indictment. “The government was more frustrating than the cancer itself.” The Ressel family traveled to Washington DC to meet hundreds of other Burzynski patients to speak out against the FDA’s attempt to remove him from society.

Family Speaks Out

Jessica Ressel’s medical records are published by written authorization by Jessica Ressel-Doeden.


Sophia Gettino – Pinealoblastoma – Cured with Medical Records

Sophia Gettino Pinealoblastoma Cured


Sophia Gettino was diagnosed with a pinealoblastoma brain tumor on December 18, 1996—when she was 10 months old. [1]

Sophia was born in January 1996. In December of 1996, Sophia’s parents noticed that she was having trouble with her motor skills, displaying a decrease in appetite, and had noticeable swelling of the head.

After several visits to the pediatrician’s office, they decided to have an MRI conducted to see if anything was wrong with her brain. The MRI revealed a mass measuring nearly 3 cm in her brain. On December 18, 1996 a biopsy was performed by the pathology department at the Syracuse Health Center in Syracuse, New York—which diagnosed Sophia with a deadly pinealoblastoma brain tumor.

On December 20, 1996 surgeons at the Syracuse Health Center removed nearly all of her tumor, but were unable to remove it all without injuring Sophia any further.

In their evaluation report oncologists at Syracuse stated “Because of her age, short onset of symptoms and pathologic findings, her prognosis unfortunately is very poor. The option of chemotherapy was presented to the family.”

The chemotherapy offered to Sophia was a combination of thiotepa, etoposide, and carboplatine.

Thiotepa Chemotherapy was approved by the FDA on March 9, 1959. This drug was approved for breast, ovary, and bladder cancer primarily. To date, thiotepa’s “safety and effectiveness in pediatric patients have not been established.” The expected side effects of this chemotherapy in non-pediatric patients are: low blood cell count, vomiting, infertility, hair loss, blurred vision, and being a carcinogen causes more cancer.

Etoposide Chemotherapy was approved by the FDA on November 11, 1983. This drug is used to treat people with testicular cancer or small cell lung cancer. In pediatric patients, etoposide’s “safety and efficacy have not been established”. The side effects in non-pediatric patients receiving this therapy include leukemia, nerve damage, inability to fight infections, and vomiting. There is limited evidence to verify whether or not this drug used alone causes more cancer, but there is sufficient evidence that when used with other chemotherapy that is does cause cancer.

Carboplatine Chemotherapy was approved in the late 1980’s and is primarily used to treat ovarian, lung, and head and neck cancers. “the most troubling effects of carboplatin tends to be damage to the bone marrow…” Other side effects include damage to the nervous system, mouth sores, loss of appetite, stomach pain, diarrhea, vomiting, and changes in vision.

After understanding that these chemotherapeutic drugs would not likely save Sophia, combined with the side effects this chemotherapy regimen could cause to their daughter, Sophia’s parents declined all chemotherapy treatment offered by their oncologists and decided to explore other methods of treatment. Upon this search for another option they found the Burzynski Clinic.

On February 27, 1997 Sophia was admitted for antineoplaston therapy in a FDA-supervised Phase II clinical trial. She discontinued antineoplaston therapy on March 7, 2003 due to a complete response. She is alive, healthy, and remains cancer-free today. (A residual, benign tumor is still left in her brain, but all signs of malignancy have disappeared and have not returned to date).

Medical Records

Diagnosis:
1. December 18, 1996 pathology report from Syracuse Health Center.
2. December 25, 1996 Syracuse Health oncology evaluation report verifying diagnosis, with suggested experimental chemotherapy regimen.
Baseline MRI of the brain on February 26, 1997 showing a massive tumor in her brain.

Recovery:
4. Sophia’s Phase II FDA-clinical trial treatment summary
5. Tumor Measurements from start of treatment to declaration of “complete response”.
6. A third party confirmation of complete response from J.C. Pleasure, MD of Oncoimaging, P.A. in Herdon, VA
7. February 3, 2003 MRI scan showing the residual benign remnants of the once malignant tumor.

Comparing the FDA clinical trial data for this type of tumor

In a group of Phase II clinical trials using only Antineoplastons, with 13 children ranging from one to eleven years old with PNET tumors: Six of those patients (46%) survived more than 5 years after treatment. Five of the six patients had not undergone any previous chemotherapy or radiation prior to being treated with Antineoplastons. Click here to read this study’s abstract.

In contrast, a chemotherapy drug produced by GlaxoSmithKline called Topotecan (also a gene-targeted drug), is undergoing Phase II trials for this type of tumor in children as well. Twenty-six children were treated, two objective responses were noted (7.6%), and these two patients managed to live beyond five years. However, this does not indicate the damage, if any, this chemotherapeutic drug caused these patients. Click here to read this study.

Therefore, in virtually identical Phase II gene-targeted clinical trials treating PNET in children: topotecan chemotherapy resulted in a 7.6% 5-year survival; while Antineoplastons resulted a 46% 5-year survival. It’s important to note that while Antineoplastons are free of harmful side effects, topotecan’s side effects generally include: hair loss, vomiting, and diarrhea—if you are lucky. If you are one that has a more severe reaction to this drug, the side effects can include: difficulty breathing; swelling of the face, lips and tongue; severe cough; painful urination, unexplained bruising, and stomach cramps. Click here more on this drug.

Sophia Gettino’s medical records are published by written authorization by her family.

Susan Hale – Glioblastoma Multiforme Grade IV – Cured – with Medical Records

To fully utilize this article, click on the blue text to link to the source being discussed.

Susan Hale was diagnosed with a Glioblastoma Multiforme Grade IV brain tumor (which measured the size of a golf ball) in May, 1997 at 45 years old. After all other treatment failed, she began Antineoplaston treatment on August 10, 1998 and four months later she was cancer free. Susan Hale has been alive and cancer-free ever since.

Medical Records

#1 Diagnosis – After suffering from severe weakness and headaches, Susan Hale was admitted into the Torrence Medical Center Emergency Room in May, 1997 and an MRI was ordered by the on-call ER physician. The MRI revealed a tumor in the temporoparietal region on the right side of her brain. A craniotomy (surgery) to remove the tumor and a biopsy was performed by the Torrence pathologists and they diagnosed her with Glioblastoma Multiforme Grade IV brain cancer. [read May 5, 1997 pathology report – PDF].

#2 Prior Treatment – After the first May 1997 surgery failed to remove all of her tumor, Susan underwent 6 weeks of standard radiation treatment from May 12, 1997 to June 27, 1997. After radiation treatment failed to affect the tumor, Susan underwent gamma knife radiation on October 28, 1997. A followup MRI in February 1998 reported no change in her tumor. Another MRI in May 1998 revealed the tumor was still growing. Surgeons and Oncologists recommended a second craniotomy (surgery) which was performed on June 3, 1998 at USC University Hospital—which again only removed part of the tumor. Within a month another MRI revealed that the tumor was still growing. Surgeons advised surgery a third time, in which Susan Hale declined and decided to investigate other “outside” therapies. Despite two surgeries, a full course of standard radiation and gamma knife radiation, Susan Hale’s tumor continued to progress.

#3 Recovery – Susan Hale began Antineoplaston treatment on August 10, 1998. [view 7/30/98 Baseline MRI image]. Within four months of Antineoplaston treatment her cancer was gone. [view 12/8/98 MRI image] [Feb. 2009 MRI showing no recurrence of the tumor over ten years later – image]

#4 Treating Glioblastoma Multiforme Grade IV without using Antineoplastons – In December 2010, some German scientists have admitted total defeat: “For patients with relapsed GBM [Glioblastoma Multiforme] there is currently no standard systemic therapy.”

The New England Journal of Medicine Published a study from 2005 stated: “Glioblastoma, the most common primary brain tumor in adults, is usually rapidly fatal. The current standard of care for newly diagnosed glioblastoma is surgical resection to the extent feasible, followed by adjuvant radiotherapy. In this trial we compared radiotherapy alone with radiotherapy plus temozolomide [Temodar®], given concomitantly with and after radiotherapy, in terms of efficacy and safety.” This is the same treatment Mr. Treadwell received prior to begin treated with Antineoplastons.

#5 FDA supervised clinical trial data comparing radiation, chemotherapy, and gene-targeted therapy (other than Antineoplastons) to Antineoplaston therapy for Glioblastoma Multiforme Grade IV – Radiation & Chemotherapy in 798 patients = 0% 5-year survival; Gene-targeted drugs other than Antineoplastons in 671 patients = 0% 5-year survival; 368 patients treated with Antineoplastons = 5.25% survival. [Read the full report – PDF].

It should be noted that Senator Ted Kennedy died of Glioblastoma Grade IV brain cancer. Countless Glioblastoma survivors cured by Antineoplastons as well as many other people cured of other types of cancer due to Antineoplastons flooded Kennedy’s office to share with him the existence of Antineoplastons. Mr. Kennedy’s wife wrote the Burzynski’s Clinic requesting all communication from Antineoplaston treated cancer survivors stop contacting his office entirely. A year later, Kennedy was dead.

Susan Hale’s medical records are published by written authorization by Susan Hale.